Deaconescu Laboratory

RssB Is a Shape-shifter!

Structure of RssB bound to berrylofluoride or anti-adaptors

Phosphorylated-like RssB

RssB receiver domain bound to beryllofluoride (PDB ID 7LCM)

Cryp-EM reconstruction of DNA-bound Mfd

IraD-bound RssB

Spastin-treated microtubules

Hmf1

PDB ID 1JD1

Microtubules

Negative Stain Electron Microscopy

SAXS Envelope of Mfd

Tubulin Sheets

Imaged by electron microscopy in negative stain

Structure of Mfd

PDB ID 2EYQ

Ring Stacks

Acetyltransferase TAT induces stacking of tubulin rings. Imaged ny electron microscopy in negative stain

Structure of a Core UvrA-Mfd complex

Obtained by X-ray crystallography (PDB ID 4DFC)

Dolastatin tubulin rings

Imaged by electron microscopy in negative stain